Neuroscience studies of human decision-making abilities commonly involve subjects completing a decision-making task while BOLD signals are recorded using fMRI. Hypotheses are tested about which brain regions mediate the effect of past experience, such as rewards, on future actions. One standard approach to this is model-based fMRI data analysis, in which a model is fitted to the behavioral data, i.e., a subject's choices, and then the neural data are parsed to find brain regions whose BOLD signals are related to the model's internal signals. However, the internal mechanics of such purely behavioral models are not constrained by the neural data, and therefore might miss or mischaracterize aspects of the brain. To address this limitation, we introduce a new method using recurrent neural network models that are flexible enough to be jointly fitted to the behavioral and neural data. We trained a model so that its internal states were suitably related to neural activity during the task, while at the same time its output predicted the next action a subject would execute. We then used the fitted model to create a novel visualization of the relationship between the activity in brain regions at different times following a reward and the choices the subject subsequently made. Finally, we validated our method using a previously published dataset. We found that the model was able to recover the underlying neural substrates that were discovered by explicit model engineering in the previous work, and also derived new results regarding the temporal pattern of brain activity.

Working memory is a central cognitive ability crucial for intelligent decision-making. Recent experimental and computational work studying working memory has primarily used categorical (i.e., one-hot) inputs, rather than ecologically-relevant, multidimensional naturalistic ones. Moreover, studies have primarily investigated working memory during single or few number of cognitive tasks. As a result, an understanding of how naturalistic object information is maintained in working memory in neural networks is still lacking. To bridge this gap, we developed sensory-cognitive models, comprising of a convolutional neural network (CNN) coupled with a recurrent neural network (RNN), and trained them on nine distinct N-back tasks using naturalistic stimuli. By examining the RNN's latent space, we found that: 1) Multi-task RNNs represent both task-relevant and irrelevant information simultaneously while performing tasks; 2) While the latent subspaces used to maintain specific object properties in vanilla RNNs are largely shared across tasks, they are highly task-specific in gated RNNs such as GRU and LSTM; 3) Surprisingly, RNNs embed objects in new representational spaces in which individual object features are less orthogonalized relative to the perceptual space; 4) Interestingly, the transformation of WM encodings (i.e., embedding of visual inputs in the RNN latent space) into memory was shared across stimuli, yet the transformations governing the retention of a memory in the face of incoming distractor stimuli were distinct across time.

Neuroscience studies of human decision-making abilities commonly involve subjects completing a decision-making task while BOLD signals are recorded using fMRI. Hypotheses are tested about which brain regions mediate the effect of past experience, such as rewards, on future actions. One standard approach to this is model-based fMRI data analysis, in which a model is fitted to the behavioral data, i.e., a subject's choices, and then the neural data are parsed to find brain regions whose BOLD signals are related to the model's internal signals. However, the internal mechanics of such purely behavioral models are not constrained by the neural data, and therefore might miss or mischaracterize aspects of the brain. To address this limitation, we introduce a new method using recurrent neural network models that are flexible enough to be jointly fitted to the behavioral and neural data.

In this paper the authors use a recurrent neural network model to study reward processing in human fMRI experiments. The main novelty of this approach is that it takes into account both the neural data (measured by fMRI) and the behavioral outcomes. In contrast the standard approach is to fit a computational model on the behavioral data, then use that as a regressor in a classical GLM analysis, which may find a good solution for the behavioral data but one that is different from the solution implemented in the brain. In this respect, this application stands out. Most other neural network models that are used to model fMRI data (e.g.

This paper investigates the forecasting performance of COMEX copper futures realized volatility across various high-frequency intervals using both econometric volatility models and deep learning recurrent neural network models. The econometric models considered are GARCH and HAR, while the deep learning models include RNN (Recurrent Neural Network), LSTM (Long Short-Term Memory), and GRU (Gated Recurrent Unit). In forecasting daily realized volatility for COMEX copper futures with a rolling window approach, the econometric models, particularly HAR, outperform recurrent neural networks overall, with HAR achieving the lowest QLIKE loss function value. However, when the data is replaced with hourly high-frequency realized volatility, the deep learning models outperform the GARCH model, and HAR attains a comparable QLIKE loss function value. Despite the black-box nature of machine learning models, the deep learning models demonstrate superior forecasting performance, surpassing the fixed QLIKE value of HAR in the experiment. Moreover, as the forecast horizon extends for daily realized volatility, deep learning models gradually close the performance gap with the GARCH model in certain loss function metrics. Nonetheless, HAR remains the most effective model overall for daily realized volatility forecasting in copper futures.

A three-layered neural network model was used to explore the organization of the vestibulo-ocular reflex (VOR). The dynamic model was trained using recurrent back-propagation to produce compensatory, long duration eye muscle motoneuron outputs in response to short duration vestibular afferent head velocity inputs. The network learned to produce this response prolongation, known as velocity storage, by developing complex, lateral inhibitory interac(cid:173) tions among the interneurons. These had the low baseline, long time constant, rectified and skewed responses that are characteristic of real VOR inter(cid:173) neurons. The model suggests that all of these features are interrelated and result from lateral inhibition.

MIT and Austrian researchers have created "liquid" machine learning for a flexible artificial intelligence. A novel class of artificial intelligence (AI) machine learning will be unveiled at the upcoming Thirty-Fifth AAAI Conference on Artificial Intelligence in early February 2021. Massachusetts Institute of Technology (MIT) and Austrian researchers have created a new neural network endowed with increased fluid artificial intelligence called "liquid" machine learning. This new class of machine learning may enable better adaptation to dynamic fluctuations of complex, real-world problems. In areas where data streams change over time, developing more flexible AI that can learn quickly is mission-critical.

Neural differential equations are a promising new member in the neural network family. They show the potential of differential equations for time series data analysis. In this paper, the strength of the ordinary differential equation (ODE) is explored with a new extension. The main goal of this work is to answer the following questions: (i)~can ODE be used to redefine the existing neural network model? (ii)~can Neural ODEs solve the irregular sampling rate challenge of existing neural network models for a continuous time series, i.e., length and dynamic nature, (iii)~how to reduce the training and evaluation time of existing Neural ODE systems? This work leverages the mathematical foundation of ODEs to redesign traditional RNNs such as Long Short-Term Memory (LSTM) and Gated Recurrent Unit (GRU). The main contribution of this paper is to illustrate the design of two new ODE-based RNN models (GRU-ODE model and LSTM-ODE) which can compute the hidden state and cell state at any point of time using an ODE solver. These models reduce the computation overhead of hidden state and cell state by a vast amount. The performance evaluation of these two new models for learning continuous time series with irregular sampling rate is then demonstrated. Experiments show that these new ODE based RNN models require less training time than Latent ODEs and conventional Neural ODEs. They can achieve higher accuracy quickly, and the design of the neural network is simpler than, previous neural ODE systems.

Neuroscience studies of human decision-making abilities commonly involve subjects completing a decision-making task while BOLD signals are recorded using fMRI. Hypotheses are tested about which brain regions mediate the effect of past experience, such as rewards, on future actions. One standard approach to this is model-based fMRI data analysis, in which a model is fitted to the behavioral data, i.e., a subject's choices, and then the neural data are parsed to find brain regions whose BOLD signals are related to the model's internal signals. However, the internal mechanics of such purely behavioral models are not constrained by the neural data, and therefore might miss or mischaracterize aspects of the brain. To address this limitation, we introduce a new method using recurrent neural network models that are flexible enough to be jointly fitted to the behavioral and neural data.

Electronic Medical Records (EMR) are a rich source of patient information, including measurements reflecting physiologic signs and administered therapies. Identifying which variables are useful in predicting clinical outcomes can be challenging. Advanced algorithms such as deep neural networks were designed to process high-dimensional inputs containing variables in their measured form, thus bypass separate feature selection or engineering steps. We investigated the effect of extraneous input variables on the predictive performance of Recurrent Neural Networks (RNN) by including in the input vector extraneous variables randomly drawn from theoretical and empirical distributions. RNN models using different input vectors (EMR variables; EMR and extraneous variables; extraneous variables only) were trained to predict three clinical outcomes: in-ICU mortality, 72-hour ICU re-admission, and 30-day ICU-free days. The measured degradations of the RNN's predictive performance with the addition of extraneous variables to EMR variables were negligible.